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IR415
CAS No. 452967-14-5
IR415 ( IR 415;IR-415 )
Catalog No. M14538 CAS No. 452967-14-5
IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | Get Quote |
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| 5MG | 58 | Get Quote |
|
| 10MG | 102 | Get Quote |
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| 25MG | 205 | Get Quote |
|
| 50MG | 357 | Get Quote |
|
| 100MG | 530 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameIR415
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NoteResearch use only, not for human use.
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Brief DescriptionIR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression.
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DescriptionIR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression, reverses the inhibitory effect of HBx protein on activity of the Dicer endoribonuclease; exhibits a marked depletion of HBV core protein synthesis and down-regulation of pre-genomic HBV RNA in HBV-infected HepG2 cells, selectively targets HBx in a concentration-dependent manner.
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SynonymsIR 415;IR-415
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PathwayMicrobiology/Virology
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TargetHBV
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RecptorHBV
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Research Area——
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Indication——
Chemical Information
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CAS Number452967-14-5
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Formula Weight296.34
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Molecular FormulaC13H14F2N4S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN-(2,4-difluorophenyl)-N'-[3-(1H-imidazol-1-yl) propyl] thiourea
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ghosh S, et al. J Biol Chem. 2017 Jul 28;292(30):12577-12588.
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