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IMB-301

CAS No. 64009-84-3

IMB-301 ( IMB301;NSC 301209 )

Catalog No. M15432 CAS No. 64009-84-3

IMB-301 (NSC 301209) is a small molecule inhibitor that target the binding interface of the HIV-1 Vif/hA3G complex.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 178 Get Quote
10MG 295 Get Quote
25MG 502 Get Quote
50MG 709 Get Quote
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Biological Information

  • Product Name
    IMB-301
  • Note
    Research use only, not for human use.
  • Brief Description
    IMB-301 (NSC 301209) is a small molecule inhibitor that target the binding interface of the HIV-1 Vif/hA3G complex.
  • Description
    IMB-301 (NSC 301209) is a small molecule inhibitor that target the binding interface of the HIV-1 Vif/hA3G complex, inhibits the replication of HIV-1 in H9 cells (IC50=8.63 uM); restores hA3G expression in the presence of Vif through disruption of the Vif-hA3G interaction, significantly increases the amount of hA3G-HA in the virions; directly binds to hA3G with of 15.6 uM.
  • Synonyms
    IMB301;NSC 301209
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    64009-84-3
  • Formula Weight
    379.26
  • Molecular Formula
    C19H17Cl2FN2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1=CC(=CC=C1OCCC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)F
  • Chemical Name
    1-(2-(2,4-dichlorophenyl)-4-(4-fluorophenoxy)butyl)-1H-imidazole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ma L, et al. Sci Rep. 2018 May 23;8(1):8067.
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