ICA-105574

CAS No. 316146-57-3

ICA-105574 ( ICA; 3-nitro-N-[4-phenoxyphenyl]-benzamide )

Catalog No. M24250 CAS No. 316146-57-3

ICA-105574 is an activator of hERG that binds to the channel to remove inactivation, thus increasing peak current amplitude and shortening the action potential. It also modulates activation kinetics of the channel.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 76 In Stock
10MG 132 In Stock
25MG 282 In Stock
50MG 444 In Stock
100MG 651 In Stock
500MG 1368 In Stock
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Biological Information

  • Product Name
    ICA-105574
  • Note
    Research use only, not for human use.
  • Brief Description
    ICA-105574 is an activator of hERG that binds to the channel to remove inactivation, thus increasing peak current amplitude and shortening the action potential. It also modulates activation kinetics of the channel.
  • Description
    ICA-105574 is an activator of hERG that binds to the channel to remove inactivation, thus increasing peak current amplitude and shortening the action potential. It also modulates activation kinetics of the channel.
  • Synonyms
    ICA; 3-nitro-N-[4-phenoxyphenyl]-benzamide
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    hERG
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    316146-57-3
  • Formula Weight
    334.3
  • Molecular Formula
    C19H14N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C1=CC=C(C=C1)OC2=CC=C(C=C2)NC(=O)C3=CC(=CC=C3)[N+](=O)[O-]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Meng J , Shi C , Li L , et al. Compound ICA-105574 prevents arrhythmias induced by cardiac delayed repolarization[J]. European Journal of Pharmacology, 2013, 718(1-3):87-97.
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