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I3MT-3
CAS No. 459420-09-8
I3MT-3( HMPSNE )
Catalog No. M24410 CAS No. 459420-09-8
I3MT-3 (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 155 | In Stock |
|
| 10MG | 245 | In Stock |
|
| 25MG | 492 | In Stock |
|
| 50MG | 710 | In Stock |
|
| 100MG | 972 | In Stock |
|
| 500MG | 1971 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameI3MT-3
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NoteResearch use only, not for human use.
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Brief DescriptionI3MT-3 (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST.
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DescriptionI3MT-3 (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST.
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In VitroCell Proliferation Assay Cell Line:CT26 cells Concentration:0 μM; 10 μM; 30 μM; 100 μM; 300 μM Incubation Time:48 hours Result:Slowed down proliferation of CT26 cells.
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In Vivo——
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SynonymsHMPSNE
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PathwayWnt/Notch/Hedgehog
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TargetHippo
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RecptorMST3
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Research Area——
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Indication——
Chemical Information
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CAS Number459420-09-8
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Formula Weight310.4
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Molecular FormulaC17H14N2O2S
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Purity>98% (HPLC)
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SolubilityDMSO:120mg/mL (386.64mM)
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SMILESO=C1NC(SCC(C2=C3C=CC=CC3=CC=C2)=O)=NC(C)=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hanaoka K, Sasakura K, Suwanai Y, et al. Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide. Sci Rep. 2017;7:40227. Published 2017 Jan 12. doi:10.1038/srep40227
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I3MT-3
I3MT-3 (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST.
