Hedgehog-IN-7d

CAS No. 330796-24-2

Hedgehog-IN-7d( Hh Antagonist VIII )

Catalog No. M14103 CAS No. 330796-24-2

Hedgehog-IN-7d is a potent, cell-permeable Hedgehog (Hh) pathway inhibitor that inhibits Gli transcription activity with an IC50 value of 70 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Hedgehog-IN-7d
  • Note
    Research use only, not for human use.
  • Brief Description
    Hedgehog-IN-7d is a potent, cell-permeable Hedgehog (Hh) pathway inhibitor that inhibits Gli transcription activity with an IC50 value of 70 nM.
  • Description
    Hedgehog-IN-7d is a potent, cell-permeable Hedgehog (Hh) pathway inhibitor that inhibits Gli transcription activity with an IC50 value of 70 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Hh Antagonist VIII
  • Pathway
    Wnt/Notch/Hedgehog
  • Target
    Gli
  • Recptor
    Gli
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    330796-24-2
  • Formula Weight
    490.8
  • Molecular Formula
    C23H15ClF4N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1=CC=C2C(=C1)C(=O)N(C(=N2)CNC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)C4=CC=C(C=C4)F
  • Chemical Name
    N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]-urea

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brunton SA, et al. J Med Chem. 2008 Mar 13;51(5):1108-10.
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