Cart
sales@molnova.com
Glemanserin
CAS No. 107703-78-6
Glemanserin( —— )
Catalog No. M33884 CAS No. 107703-78-6
Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 52 | Get Quote |
|
| 5MG | 76 | Get Quote |
|
| 10MG | 122 | Get Quote |
|
| 25MG | 264 | Get Quote |
|
| 50MG | 419 | Get Quote |
|
| 100MG | 605 | Get Quote |
|
| 500MG | 1287 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameGlemanserin
-
NoteResearch use only, not for human use.
-
Brief DescriptionGlemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.
-
DescriptionGlemanserin (MDL11939) is a potent and selective antagonist for serotonin receptor 5-HT2A (Ki=2.89, 0.54 and 2.5 nM for rat 5-HT2A, rabbit 5-HT2A and human 5-HT2A, respectively).
-
In Vitro——
-
In VivoGlemanserin (MDL11939) suppressesthe induced increase in locomotor activity, behavioral sensitization and withdrawal symptoms in male mice.
-
Synonyms——
-
PathwayGPCR/G Protein
-
Target5-HT Receptor
-
Recptor5-HT Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number107703-78-6
-
Formula Weight295.42
-
Molecular FormulaC20H25NO
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (338.50 mM; Ultrasonic )
-
SMILESOC(C1CCN(CCc2ccccc2)CC1)c1ccccc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Pehek EA, et al. Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex. Neuropsychopharmacology. 2006;31(2):265-277. ?
molnova catalog
related products
-
Nelotanserin
A potent, selective 5-HT2A inverse agonist with pKi of 9.2; displays >30- and 5000-fold selectivity compared with 5-HT2C and 5-HT2B receptors.
-
DSP-1053
DSP-1053 is a novel potent serotonin reuptake (SERT) inhibitor with 5-HT1A partial agonistic activity that binds to human serotonin transporter and 5-HT1A receptor with Ki of 1.02 and 5.05 nM, respectively.
-
Didesmethyl caripraz...
Didesmethyl cariprazine, a metabolite of Cariprazine, is the major cyclic active part. Didesmethyl cariprazine has a long half-life of 1-3 weeks.
