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GWJ-A-23
CAS No. 1351930-95-4
GWJ-A-23( GWJ-23 | GWJ23 )
Catalog No. M11425 CAS No. 1351930-95-4
GWJ-A-23 (GWJ-23, GWJ23) is a?potent, selective autotaxin inhibitor with Ki of 18 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameGWJ-A-23
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NoteResearch use only, not for human use.
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Brief DescriptionGWJ-A-23 (GWJ-23, GWJ23) is a?potent, selective autotaxin inhibitor with Ki of 18 nM.
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DescriptionGWJ-A-23 (GWJ-23, GWJ23) is a?potent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound; reduces lung collagen, bronchoalveolar lavage cell counts, total protein, LPA, and TGF-β levels, attenuates the pathogenesis of pulmonary fibrosis in vivo.
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In Vitro——
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In Vivo——
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SynonymsGWJ-23 | GWJ23
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PathwayWnt/Notch/Hedgehog
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TargetAutotaxin
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RecptorAutotaxin
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Research Area——
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Indication——
Chemical Information
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CAS Number1351930-95-4
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Formula Weight385.14
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Molecular FormulaC17H28NO4P
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCCCCCCCC(=O)NC1=CC=C(C=C1)CP(=O)([O-])[O-].[Na+].[Na+]
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Chemical Name4-(decanoylamino)benzyl]phosphonic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jiang G, et al. Bioorg Med Chem Lett. 2011 Sep 1;21(17):5098-101.
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