Cart
sales@molnova.com
GWJ-A-23
CAS No. 1351930-95-4
GWJ-A-23 ( GWJ-23;GWJ23 )
Catalog No. M11425 CAS No. 1351930-95-4
GWJ-A-23 (GWJ-23, GWJ23) is apotent, selective autotaxin inhibitor with Ki of 18 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameGWJ-A-23
-
NoteResearch use only, not for human use.
-
Brief DescriptionGWJ-A-23 (GWJ-23, GWJ23) is apotent, selective autotaxin inhibitor with Ki of 18 nM.
-
DescriptionGWJ-A-23 (GWJ-23, GWJ23) is apotent, selective autotaxin inhibitor with Ki of 18 nM, an analog of the known ATX inhibitor S32826 and has improved aqueous solubility compared with the parent compound; reduces lung collagen, bronchoalveolar lavage cell counts, total protein, LPA, and TGF-β levels, attenuates the pathogenesis of pulmonary fibrosis in vivo.
-
SynonymsGWJ-23;GWJ23
-
PathwayWnt/Notch/Hedgehog
-
TargetAutotaxin
-
RecptorAutotaxin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1351930-95-4
-
Formula Weight385.14
-
Molecular FormulaC17H28NO4P
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCCCCCCCCCC(=O)NC1=CC=C(C=C1)CP(=O)([O-])[O-].[Na+].[Na+]
-
Chemical Name4-(decanoylamino)benzyl]phosphonic acid
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jiang G, et al. Bioorg Med Chem Lett. 2011 Sep 1;21(17):5098-101.
molnova catalog
related products
-
PAT-505
PAT-505 (PAT 505, PAT505) is a potent, selective, noncompetitive, and orally active autotaxin inhibitor with IC50 of 2.0 nM against the lysoPLD activity of human ATX.
-
GLPG-1690
GLPG-1690 (Ziritaxestat, GLPG1690) is a first-in-class, potent, competitive autotaxin inhibitor with Ki/IC50 of 15 nM/131 nM.
-
GWJ-A-23
GWJ-A-23 (GWJ-23, GWJ23) is apotent, selective autotaxin inhibitor with Ki of 18 nM.
