GTP-14564( —— )

Catalog No. M36386 CAS No. 34823-86-4

GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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2MG	59	In Stock
5MG	93	In Stock
10MG	169	In Stock
25MG	334	In Stock
50MG	532	In Stock
100MG	750	In Stock
500MG	1521	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

GTP-14564
Note

Research use only, not for human use.
Brief Description

GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.
Description

GTP-14564 is a tyrosine kinase inhibitor targeting to internal tandem duplication (ITD) and FLT3. GTP-14564 inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Tyrosinase
Recptor

Tyrosine Kinases | FLT
Research Area

——
Indication

——

Chemical Information

CAS Number

34823-86-4
Formula Weight

234.25
Molecular Formula

C15H10N2O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (533.62 mM; Ultrasonic (<60°C)
SMILES

C12=C(C=3C(O1)=CC=CC3)NN=C2C4=CC=CC=C4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Murata K, et al. Selective cytotoxic mechanism of GTP-14564, a novel tyrosine kinase inhibitor in leukemia cells expressing a constitutively active Fms-like tyrosine kinase 3 (FLT3). J Biol Chem. 2003 Aug 29;278(35):32892-8.?

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