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GSK3326595
CAS No. 1616392-22-3
GSK3326595 ( GSK-3326595;EPZ015938;EPZ-015938 )
Catalog No. M12361 CAS No. 1616392-22-3
A potent, selective, reversible and orally active PRMT5 inhibitor with IC50 of 22 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
|
| 10MG | 50 | In Stock |
|
| 25MG | 98 | In Stock |
|
| 50MG | 177 | In Stock |
|
| 100MG | 332 | In Stock |
|
| 200MG | 440 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK3326595
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective, reversible and orally active PRMT5 inhibitor with IC50 of 22 nM.
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DescriptionA potent, selective, reversible and orally active PRMT5 inhibitor with IC50 of 22 nM; potently inhibits tumor growth in cellular and animal models.Blood Cancer Phase 1 Clinical
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SynonymsGSK-3326595;EPZ015938;EPZ-015938
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorHMTase
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Research AreaCancer
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IndicationBlood cancer
Chemical Information
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CAS Number1616392-22-3
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Formula Weight452.55
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Molecular FormulaC24H32N6O3
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 30 mg/mL
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SMILESO=C(C)N1CCC(NC2=NC=NC(C(NC[C@H](O)CN3CCC(C=CC=C4)=C4C3)=O)=C2)CC1
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Chemical Name4-Pyrimidinecarboxamide, 6-[(1-acetyl-4-piperidinyl)amino]-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Drew Rasco, et al. Abstract CT038, AACR. DOI: 10.1158/1538-7445.
2. Patent WO 2016022605 A1, Formula A.
2. Patent WO 2016022605 A1, Formula A.
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