GR-64349

CAS No. 137593-52-3

GR-64349 ( GR64349 )

Catalog No. M11556 CAS No. 137593-52-3

GR-64349 is a potent and selective tachykinin NK2 receptor agonist with EC50 of 3.7 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GR-64349
  • Note
    Research use only, not for human use.
  • Brief Description
    GR-64349 is a potent and selective tachykinin NK2 receptor agonist with EC50 of 3.7 nM.
  • Description
    GR-64349 is a potent and selective tachykinin NK2 receptor agonist with EC50 of 3.7 nM, displays >1000- and >300-fold selectivity over NK1 and NK3 receptors, respectively.Pain Discontinued
  • Synonyms
    GR64349
  • Pathway
    GPCR/G Protein
  • Target
    Neurokinin Receptor
  • Recptor
    Neurokinin Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    137593-52-3
  • Formula Weight
    921.12
  • Molecular Formula
    C42H68N10O11S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)CC(C(=O)NC(CCSC)C(=O)N)N1CCC(C1=O)NC(=O)C(C(C)C)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)N
  • Chemical Name
    KDSFVGLM (Modifications: Leu-7 = R-γ-lactam-Leu, Met-8 = C-terminal amide)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Deal MJ, et al. J Med Chem. 1992 Oct 30;35(22):4195-204.
2. Chizh BA, et al. Br J Pharmacol. 1995 Jul;115(6):1013-9.
3. Chang Y, et al. J Pharmacol Exp Ther. 2000 Jul;294(1):147-54.
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