Maropitant
CAS No. 147116-67-4
Maropitant ( —— )
Catalog No. M20648 CAS No. 147116-67-4
Maropitant is a selective neurokinin (NK1) receptor antagonist.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
2MG | 39 | In Stock |
|
5MG | 65 | In Stock |
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10MG | 110 | In Stock |
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25MG | 177 | In Stock |
|
50MG | 335 | In Stock |
|
100MG | 500 | In Stock |
|
500MG | 1098 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameMaropitant
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NoteResearch use only not for human use.
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Brief DescriptionMaropitant is a selective neurokinin (NK1) receptor antagonist.
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DescriptionMaropitant is a selective neurokinin (NK1) receptor antagonist.
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Synonyms——
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PathwayGPCR/G Protein
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TargetNeurokinin Receptor
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RecptorNK1
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Research Area——
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Indication——
Chemical Information
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CAS Number147116-67-4
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Formula Weight468.67
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Molecular FormulaC32H40N2O
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Purity>98% (HPLC)
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SolubilityDMSO:33.33 mg/mL (71.12 mM)
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SMILESCOc1ccc(cc1CN[C@H]1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1)C(C)(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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QWF
Tripeptide substance P (SP) antagonist (IC50 = 90 μM). Also inhibits binding of SP to Mas-related GPCR (MRGPR) X2. Inhibits SP-induced IgE-independent degranulation of mast cells in vitro. Inhibits compound 48/80-induced MRGPRX2 activation and scratching in mice in vivo.
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Eledoisin
Eledoisin is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.Eledoisin increases the value recorded under basal conditions by 24.5±3.7%; this stimulation is significantly (P<0.01) lowered to 13.1±1.9% by the simultaneous presence of CP99994.
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Fezolinetant
A potent, selective, orally active neurokinin-3 receptor (NK3R) antagonist with pIC50/pKi of 7.7/7.6.