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GNE-207
CAS No. 2158266-58-9
GNE-207 ( GNE207;GNE 207 )
Catalog No. M13443 CAS No. 2158266-58-9
GNE-207 (GNE207) is a novel potent, selective, orally active CBP/p300 bromodomain with IC50 of 1.0 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 732 | Get Quote |
|
| 50MG | 2502 | Get Quote |
|
| 100MG | 3330 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGNE-207
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NoteResearch use only, not for human use.
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Brief DescriptionGNE-207 (GNE207) is a novel potent, selective, orally active CBP/p300 bromodomain with IC50 of 1.0 nM.
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DescriptionGNE-207 (GNE207) is a novel potent, selective, orally active CBP/p300 bromodomain with IC50 of 1.0 nM; displays >2,500-fold selectivity over BRD4; suppresses Myc transcript levels in MV-4-11 cellular assays with EC50 of 18 nM; exhibits a good pharmacokinetic profile.
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SynonymsGNE207;GNE 207
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number2158266-58-9
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Formula Weight510.60
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Molecular FormulaC29H30N6O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC)C1=NC=C(C2=CC3=C(C=N2)C(C4=NN(C5CCOCC5)C6=C4CN(C(C)=O)CC6)=CC=C3)C=C1
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Chemical Name5-(8-(5-acetyl-1-(tetrahydro-2H-pyran-4-yl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)isoquinolin-3-yl)-N-methylpicolinamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lai KW, et al. Bioorg Med Chem Lett. 2018 Jan 1;28(1):15-23.
molnova catalog
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