GLP-26 ( GLP26 )

Catalog No. M13398 CAS No. 2133017-36-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

GLP-26
Note

Research use only, not for human use.
Brief Description

GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM.
Description

GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM; GLP26 is a potent inhibitor of cccDNA formation and HBeAg production against the mutant core T109I, demonstrates synergistic activity with ETV in the HepAD38 system, reducing HBV DNA replication.
Synonyms

GLP26
Pathway

Microbiology/Virology
Target

HBV
Recptor

HBV
Research Area

——
Indication

——

CAS Number

2133017-36-2
Formula Weight

373.36
Molecular Formula

C19H17F2N3O3
Purity

>98% (HPLC)
Solubility

——
SMILES

CC1=C(N(C(=C1C(=O)C(=O)NCC#C)C)C)C(=O)NC2=CC(=C(C=C2)F)F
Chemical Name

N-(3,4-difluorophenyl)-1,3,5-trimethyl-4-(2-oxo-2-(prop-2-yn-1-ylamino)acetyl)-1H-pyrrole-2-carboxamide