Cart
sales@molnova.com
GAT-100
CAS No. 1663564-42-8
GAT-100 ( GAT100 )
Catalog No. M12537 CAS No. 1663564-42-8
GAT-100 (GAT100) is a potent, selective CB1R negative allosteric modulator (NAM) with cAMP EC50 and β-arr EC50 of 174 nM and 2.1 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1053 | Get Quote |
|
| 50MG | 2142 | Get Quote |
|
| 100MG | 2790 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameGAT-100
-
NoteResearch use only, not for human use.
-
Brief DescriptionGAT-100 (GAT100) is a potent, selective CB1R negative allosteric modulator (NAM) with cAMP EC50 and β-arr EC50 of 174 nM and 2.1 nM.
-
DescriptionGAT-100 (GAT100) is a potent, selective CB1R negative allosteric modulator (NAM) with cAMP EC50 and β-arr EC50 of 174 nM and 2.1 nM, does not exhibit inverse agonism; GAT-100 is a covalent probe for mapping structure-function correlates characteristic of the druggable CB1R allosteric space.
-
SynonymsGAT100
-
PathwayGPCR/G Protein
-
TargetCannabinoid Receptor
-
RecptorCannabinoid Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1663564-42-8
-
Formula Weight432.59
-
Molecular FormulaC25H28N4OS
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(C(N1)=C(CC)C2=C1C=CC(N=C=S)=C2)NCCC3=CC=C(N4CCCCC4)C=C3
-
Chemical Name3-Ethyl-5-isothiocyanato-N-(4-(piperidin-1-yl)phenethyl)-1H-indole-2-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Kulkarni PM, et al. J Med Chem. 2016 Jan 14;59(1):44-60.
2. Laprairie RB, et al. ACS Chem Neurosci. 2016 Jun 15;7(6):776-98.
2. Laprairie RB, et al. ACS Chem Neurosci. 2016 Jun 15;7(6):776-98.
molnova catalog
related products
-
NESS-0327
A potent, selective CB1 cannabinoid receptor antagonist with Ki of 350 fM.
-
AM251
AM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 306-fold selectivity over CB2 receptors; also potent GPR55 agonist (EC50 = 39 nM).
-
N-Oleoyl glycine
N-Oleoyl glycine, a lipoamino acid, was able to promote 3T3-L1 adipogenesis through the activation of CB1 receptor and the enhancement of insulin-mediated Akt signaling pathway.
