Floxuridine ( 5-FDU; 5-Fluorodeoxyuridine; NSC 26740; NSC 27640 )

Catalog No. M14750 CAS No. 50-91-9

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Product Name

Floxuridine
Note

Research use only, not for human use.
Brief Description

Floxuridine (5-fluorodeoxyuridine) is an oncology drug that belongs to the class known as antimetabolites with an GI50 of 5.1 μM for the inhibition of PEPT1.
Description

Floxuridine (5-fluorodeoxyuridine) is an oncology drug that belongs to the class known as antimetabolites with an GI50 of 5.1 μM for the inhibition of PEPT1.
Synonyms

5-FDU; 5-Fluorodeoxyuridine; NSC 26740; NSC 27640
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

Thymidylate synthase
Research Area

Cancer
Indication

——

CAS Number

50-91-9
Formula Weight

246.19
Molecular Formula

C9H11FN2O5
Purity

>98%(HPLC)
Solubility

Ethanol: 10 mg/mL (40.61 mM); Water: 49 mg/mL (199.03 mM); DMSO: 49 mg/mL (199.03 mM)
SMILES

O=C1NC(C(F)=CN1[C@@H]2O[C@H](CO)[C@@H](O)C2)=O
Chemical Name

5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1. Ferguson PJ, et al. Br J Pharmacol. 1999 Aug; 127(8):1777-86.

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