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TFMB-(S)-2-HG
CAS No. 1445703-64-9
TFMB-(S)-2-HG( —— )
Catalog No. M34038 CAS No. 1445703-64-9
TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase. Additionally, it significantly inhibits the EglN prolyl hydroxylases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 46 | Get Quote |
|
| 10MG | 72 | Get Quote |
|
| 25MG | 144 | Get Quote |
|
| 50MG | 233 | Get Quote |
|
| 100MG | 338 | Get Quote |
|
| 500MG | 714 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTFMB-(S)-2-HG
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NoteResearch use only, not for human use.
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Brief DescriptionTFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase. Additionally, it significantly inhibits the EglN prolyl hydroxylases.
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DescriptionTFMB-(S)-2-HG is a potent inhibitor of the 5'-methylcytosine hydroxylase TET2. TFMB-(S)-2-HG also inhibits the EglN prolyl hydroxylases. TFMB-(S)-2-HG has the potential for the research of acute myeloid leukemia (AML).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA Methyltransferase
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Research Area——
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Indication——
Chemical Information
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CAS Number1445703-64-9
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Formula Weight288.22
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Molecular FormulaC13H11F3O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (346.96 mM; Ultrasonic )
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SMILESFC(F)(F)c1cccc(COC(=O)[C@@H]2CCC(=O)O2)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Losman JA, et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. 2013;339(6127):1621-1625.?
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