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Etoricoxib
CAS No. 202409-33-4
Etoricoxib ( L-791,456; MK-0663 )
Catalog No. M13152 CAS No. 202409-33-4
Etoricoxib(MK-0663) selectively inhibited COX-2 in human whole blood assays in vitro, with an IC50 value of 1.1 ± 0.1 μM for COX-2 (LPS-induced prostaglandin E2 synthesis), compared with an IC50 value of 116 ± 8 μM for COX-1 (serum thromboxane B2 generation after clotting of the blood).
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 31 | In Stock |
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| 10MG | 45 | In Stock |
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| 25MG | 65 | In Stock |
|
| 50MG | 92 | In Stock |
|
| 100MG | 140 | In Stock |
|
| 200MG | 235 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEtoricoxib
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NoteResearch use only, not for human use.
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Brief DescriptionEtoricoxib(MK-0663) selectively inhibited COX-2 in human whole blood assays in vitro, with an IC50 value of 1.1 ± 0.1 μM for COX-2 (LPS-induced prostaglandin E2 synthesis), compared with an IC50 value of 116 ± 8 μM for COX-1 (serum thromboxane B2 generation after clotting of the blood).
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DescriptionEtoricoxib(MK-0663) selectively inhibited COX-2 in human whole blood assays in vitro, with an IC50 value of 1.1 ± 0.1 μM for COX-2 (LPS-induced prostaglandin E2 synthesis), compared with an IC50 value of 116 ± 8 μM for COX-1 (serum thromboxane B2 generation after clotting of the blood).
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SynonymsL-791,456; MK-0663
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number202409-33-4
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Formula Weight358.84
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Molecular FormulaC18H15ClN2O2S
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Purity>98%(HPLC)
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SolubilitySoluble in DMSO
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SMILESO=S(C1=CC=C(C2=CC(Cl)=CN=C2C3=CC=C(C)N=C3)C=C1)(C)=O
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Chemical Name5-Chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Capone ML, et al. Prostaglandins Others Lipid Mediat. 2007 Jan;82(1-4):85-94.
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