Mollugin

CAS No. 55481-88-4

Mollugin ( Rubimaillin; Mollugin )

Catalog No. M18804 CAS No. 55481-88-4

Mollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 In Stock
10MG 65 In Stock
50MG 178 In Stock
100MG 267 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Mollugin
  • Note
    Research use only, not for human use.
  • Brief Description
    Mollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway.
  • Description
    Mollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression.
  • Synonyms
    Rubimaillin; Mollugin
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    HER2; JAK2
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    55481-88-4
  • Formula Weight
    284.3
  • Molecular Formula
    C17H16O4
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    CC1(C=Cc2c(O1)c1ccccc1c(c2C(=O)OC)O)C
  • Chemical Name
    methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhang L, et al. Biochem Biophys Res Commun. 2014 Jul 18;450(1):247-54.
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