Mollugin
CAS No. 55481-88-4
Mollugin ( Rubimaillin; Mollugin )
Catalog No. M18804 CAS No. 55481-88-4
Mollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 35 | In Stock |
|
10MG | 65 | In Stock |
|
50MG | 178 | In Stock |
|
100MG | 267 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameMollugin
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NoteResearch use only, not for human use.
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Brief DescriptionMollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway.
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DescriptionMollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression.
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SynonymsRubimaillin; Mollugin
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorHER2; JAK2
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number55481-88-4
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Formula Weight284.3
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Molecular FormulaC17H16O4
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Purity98%
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Solubility——
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SMILESCC1(C=Cc2c(O1)c1ccccc1c(c2C(=O)OC)O)C
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Chemical Namemethyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang L, et al. Biochem Biophys Res Commun. 2014 Jul 18;450(1):247-54.
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