Paeoniflorin( NSC 178886 )

Catalog No. M13654 CAS No. 23180-57-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

Paeoniflorin
Note

Research use only, not for human use.
Brief Description

Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.
Description

Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.(In Vitro):Paeoniflorin (80 μg/mL; 4-24 h) treatment can induce Hsp40 and Hsp27 as well as Hsp70.(In Vivo):Paeoniflorin (intradermal injection; 25 and 100mg/kg; once daily; 20 days) shows favorable effects on experimental arthritis.
In Vitro

Paeoniflorin (80 μg/mL; 4-24 h) treatment can induce Hsp40 and Hsp27 as well as Hsp70. Western Blot Analysis Cell Line:HeLa and IMR-32 cells Concentration:80 μg/mL Incubation Time:4, 8, 12, 16, and 24 hours Result:Promoted the phosphorylation of HSF1.
In Vivo

Paeoniflorin (intradermal injection; 25 and 100mg/kg; once daily; 20 days) shows favorable effects on experimental arthritis. Animal Model:SD rats with collagen induced arthritis Dosage:25 and 100mg/kg Administration:Intradermal injection; 25 and 100mg/kg; once daily; 20 days Result:Decreased arthritis score, relieved ankle and paw swelling, improved spleen istopathology, decreased the levels of IgA, IgM, IgG and anti-CII antibody.
Synonyms

NSC 178886
Pathway

Chromatin/Epigenetic
Target

COX
Recptor

COX
Research Area

Inflammation/Immunology
Indication

——

CAS Number

23180-57-6
Formula Weight

480.46
Molecular Formula

C23H28O11
Purity

>98% (HPLC)
Solubility

DMSO: 96mg/ml (199.81 mM); Water: 96mg/ml (199.81 mM); Ethanol: 96mg/ml (199.81 mM)
SMILES

O[C@@H]([C@@H]([C@@H]([C@H](CO)O1)O)O)[C@H]1O[C@@]2(C3)C(C4)(C)OC5OC4(O)C3C25COC(C6=CC=CC=C6)=O
Chemical Name

beta-D-Glucopyranoside, 5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta(cd)pentalen-1a(2H)-yl, (1aR-(1a-alpha,2-beta,3a-alpha,5-alpha,5a-alpha,5b-alpha))

1.Cao BY, et al. J Ethnopharmacol, 2010. 131(1): p. 122-9.

Calculator

molnova catalog