Ergolide
CAS No. 54999-07-4
Ergolide( —— )
Catalog No. M24538 CAS No. 54999-07-4
Ergolide inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 224 | In Stock |
|
10MG | 383 | In Stock |
|
25MG | 624 | In Stock |
|
50MG | 866 | In Stock |
|
100MG | 1161 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameErgolide
-
NoteResearch use only, not for human use.
-
Brief DescriptionErgolide inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB.?
-
DescriptionErgolide inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB.?Ergolide is a sesquiterpene lactone isolated from the dried flowers of Inula Britannica.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetNF-κB
-
RecptorNF-κB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number54999-07-4
-
Formula Weight306.35
-
Molecular FormulaC17H22O5
-
Purity>98% (HPLC)
-
SolubilityDMSO:50 mg/mL (163.21 mM; Need ultrasonic)
-
SMILESC[C@H](C[C@@H]([C@H]([C@@H]1OC(C)=O)C2=C)OC2=O)[C@H](CC2)[C@@]1(C)C2=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Whan Han J, et al. Ergolide, sesquiterpene lactone from Inula britannica, inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-kappaB. Br J Pharmacol. 2001 Jun;133(4):503-12.
molnova catalog
related products
-
SR12343
SR12343 (SR-12343) is a novel NF-κB essential modulator (NEMO)-binding domain (NBD) mimetic for inhibiting IKK/NF-κB activation.
-
Scopolin
Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for angiogenesis related diseases and can serve as a structural base for screening more potent synthetic analogs.
-
Epoxyazadiradione
Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NF-kB in human cervical cancer cells.