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Deoxyelephantopin
CAS No. 29307-03-7
Deoxyelephantopin( —— )
Catalog No. M24213 CAS No. 29307-03-7
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities;?it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 222 | In Stock |
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| 10MG | 331 | In Stock |
|
| 25MG | 536 | In Stock |
|
| 50MG | 777 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDeoxyelephantopin
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NoteResearch use only, not for human use.
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Brief DescriptionDeoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities;?it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling
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DescriptionDeoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities;?it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling.
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In VitroDeoxyelephantopin inhibits the cell growth of HCT 116 (colorectal), K562 (chronic myeloid leukemia), KB (oral), and T47D (breast) cancer cell lines with IC50s of 7.46, 4.02, 3.35, 1.86 μg/mL, respectively.Deoxyelephantopin increases the expression of p53, p-JNK, and p-p38 and decreases the expression of p-STAT3 and p-mTOR in cancer cells. Deoxyelephantopin downregulates MMP-2 and MMP-9, uPA, and uPAR mRNA levels in cancer cells.
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetNF-κB
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RecptorNF-κB
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Research Area——
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Indication——
Chemical Information
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CAS Number29307-03-7
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Formula Weight344.37
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Molecular FormulaC19H20O6
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESO=C(O[C@H]([C@]([H])([C@]([H])(OC1=O)C=C(C)C2)C1=C)CC3=C[C@@]2(OC3=O)[H])C(C)=C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Evaluation of in vitro cytochrome P450 induction and inhibition activity of deoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber L.Food Chem Toxicol. 2013 Oct;60:98-108.
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