
Eniporide
CAS No. 176644-21-6
Eniporide( ENIPORIDE )
Catalog No. M12661 CAS No. 176644-21-6
eniporide is a Na(+)/H(+) exchange inhibitor.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 58 | In Stock |
![]() ![]() |
5MG | 105 | In Stock |
![]() ![]() |
10MG | 183 | In Stock |
![]() ![]() |
25MG | 311 | In Stock |
![]() ![]() |
50MG | 466 | In Stock |
![]() ![]() |
100MG | 674 | In Stock |
![]() ![]() |
200MG | Get Quote | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameEniporide
-
NoteResearch use only, not for human use.
-
Brief Descriptioneniporide is a Na(+)/H(+) exchange inhibitor.
-
Descriptioneniporide is a Na(+)/H(+) exchange inhibitor. (In Vitro):There is no significant effects of the Na+/H+ exchange inhibitor eniporide on cardiac performance and high energy phosphate content in healthy pig hearts subjected to ischemia/reperfusion induced by crystalloid cardioplegic arrest.(In Vivo):In stage 1, the administration of 100 mg and 150 mg eniporide results in smaller infarct sizes, especially in the angioplasty group. In contrast, in stage 2 there is no difference in the enzymatic infarct size between the three groups. Overall there is no effect of eniporide on clinical outcome (death, cardiogenic shock, heart failure, life-threatening arrhythmias). However, there is a significant reduction of the incidence of heart failure in patients reperfused late (>4 h).
-
In Vitro——
-
In VivoAnimal Model:Clinically relevant pig models of cardiopulmonary bypass (CPB) and cardioplegia Dosage:3 mg/kg Administration:IV; systemic infusion before cardioplegia with added 2 μM Eniporide or not Result:Had no effect on standard hemodynamics including vascular pressures and cardiac index nor for cardiac performance factors.Reduced myocardial edema and improves heart function.
-
SynonymsENIPORIDE
-
PathwayEndocrinology/Hormones
-
TargetATPase
-
RecptorNa+/K+-ATPase
-
Research AreaCardiovascular Disease
-
Indication——
Chemical Information
-
CAS Number176644-21-6
-
Formula Weight320.37
-
Molecular FormulaC14H16N4O3S
-
Purity>98% (HPLC)
-
SolubilityDMSO: 10 mM
-
SMILESO=C(/N=C(N)\N)C1=CC(S(=O)(C)=O)=C(N2C=CC=C2)C=C1C
-
Chemical NameN-(Diaminomethylene)-2-methyl-5-(methylsulfonyl)-4-(1H-pyrrol-1-yl)benzamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Zeymer U, et al. J Am Coll Cardiol. 2001 Nov 15;38(6):1644-50.
molnova catalog



related products
-
(-)-Hydroxycitric ac...
(-)-Hydroxycitric acid (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia. It is a potent and competitive inhibitor of ATP citrate lyase. (-)-Hydroxycitric acid suppresses fatty acid synthesis, food intake, lipogenesis, and induced weight loss.
-
Omecamtiv mecarbil
Omecamtiv mecarbil (CK-1827452) is the first potent cardiac myosin activator that can specifically activate the cardiac myosin S1 domain but not other muscle myosins.
-
Wilforine
Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants and is effective in treating idiopathic pulmonary fibrosis.