
Eniporide
CAS No. 176644-21-6
Eniporide( ENIPORIDE )
Catalog No. M12661 CAS No. 176644-21-6
eniporide is a Na(+)/H(+) exchange inhibitor.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 58 | In Stock |
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5MG | 105 | In Stock |
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10MG | 183 | In Stock |
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25MG | 311 | In Stock |
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50MG | 466 | In Stock |
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100MG | 674 | In Stock |
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Biological Information
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Product NameEniporide
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NoteResearch use only, not for human use.
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Brief Descriptioneniporide is a Na(+)/H(+) exchange inhibitor.
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Descriptioneniporide is a Na(+)/H(+) exchange inhibitor. (In Vitro):There is no significant effects of the Na+/H+ exchange inhibitor eniporide on cardiac performance and high energy phosphate content in healthy pig hearts subjected to ischemia/reperfusion induced by crystalloid cardioplegic arrest.(In Vivo):In stage 1, the administration of 100 mg and 150 mg eniporide results in smaller infarct sizes, especially in the angioplasty group. In contrast, in stage 2 there is no difference in the enzymatic infarct size between the three groups. Overall there is no effect of eniporide on clinical outcome (death, cardiogenic shock, heart failure, life-threatening arrhythmias). However, there is a significant reduction of the incidence of heart failure in patients reperfused late (>4 h).
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In Vitro——
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In VivoAnimal Model:Clinically relevant pig models of cardiopulmonary bypass (CPB) and cardioplegia Dosage:3 mg/kg Administration:IV; systemic infusion before cardioplegia with added 2 μM Eniporide or not Result:Had no effect on standard hemodynamics including vascular pressures and cardiac index nor for cardiac performance factors.Reduced myocardial edema and improves heart function.
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SynonymsENIPORIDE
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PathwayEndocrinology/Hormones
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TargetATPase
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RecptorNa+/K+-ATPase
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number176644-21-6
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Formula Weight320.37
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Molecular FormulaC14H16N4O3S
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESO=C(/N=C(N)\N)C1=CC(S(=O)(C)=O)=C(N2C=CC=C2)C=C1C
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Chemical NameN-(Diaminomethylene)-2-methyl-5-(methylsulfonyl)-4-(1H-pyrrol-1-yl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zeymer U, et al. J Am Coll Cardiol. 2001 Nov 15;38(6):1644-50.
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