Eniporide

CAS No. 176644-21-6

Eniporide( ENIPORIDE )

Catalog No. M12661 CAS No. 176644-21-6

eniporide is a Na(+)/H(+) exchange inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 58 In Stock
5MG 105 In Stock
10MG 183 In Stock
25MG 311 In Stock
50MG 466 In Stock
100MG 674 In Stock
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Biological Information

  • Product Name
    Eniporide
  • Note
    Research use only, not for human use.
  • Brief Description
    eniporide is a Na(+)/H(+) exchange inhibitor.
  • Description
    eniporide is a Na(+)/H(+) exchange inhibitor. (In Vitro):There is no significant effects of the Na+/H+ exchange inhibitor eniporide on cardiac performance and high energy phosphate content in healthy pig hearts subjected to ischemia/reperfusion induced by crystalloid cardioplegic arrest.(In Vivo):In stage 1, the administration of 100 mg and 150 mg eniporide results in smaller infarct sizes, especially in the angioplasty group. In contrast, in stage 2 there is no difference in the enzymatic infarct size between the three groups. Overall there is no effect of eniporide on clinical outcome (death, cardiogenic shock, heart failure, life-threatening arrhythmias). However, there is a significant reduction of the incidence of heart failure in patients reperfused late (>4 h).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Clinically relevant pig models of cardiopulmonary bypass (CPB) and cardioplegia Dosage:3 mg/kg Administration:IV; systemic infusion before cardioplegia with added 2 μM Eniporide or not Result:Had no effect on standard hemodynamics including vascular pressures and cardiac index nor for cardiac performance factors.Reduced myocardial edema and improves heart function.
  • Synonyms
    ENIPORIDE
  • Pathway
    Endocrinology/Hormones
  • Target
    ATPase
  • Recptor
    Na+/K+-ATPase
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    176644-21-6
  • Formula Weight
    320.37
  • Molecular Formula
    C14H16N4O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    O=C(/N=C(N)\N)C1=CC(S(=O)(C)=O)=C(N2C=CC=C2)C=C1C
  • Chemical Name
    N-(Diaminomethylene)-2-methyl-5-(methylsulfonyl)-4-(1H-pyrrol-1-yl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zeymer U, et al. J Am Coll Cardiol. 2001 Nov 15;38(6):1644-50.
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