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Wilforine

CAS No. 11088-09-8

Wilforine( —— )

Catalog No. M21433 CAS No. 11088-09-8

Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants and is effective in treating idiopathic pulmonary fibrosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Wilforine
  • Note
    Research use only, not for human use.
  • Brief Description
    Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants and is effective in treating idiopathic pulmonary fibrosis.
  • Description
    Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect which might be mediated by down-regulation of the expression of inflammatory factors TNF-α IL-6 and NO. It also has insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    ATPase
  • Recptor
    (NaK)-ATPase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    11088-09-8
  • Formula Weight
    867.85
  • Molecular Formula
    C43H49NO18
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (57.61 mM)
  • SMILES
    C[C@@H](CCc(nccc1)c1C(OC[C@@](C)([C@@H]([C@H]1OC(C)=O)[C@H]([C@H]2OC(C)=O)OC(C)=O)O[C@@]1([C@](C)([C@H]([C@@H]1OC(c3ccccc3)=O)O3)O)[C@]2(COC(C)=O)[C@H]1OC(C)=O)=O)C3=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhu C et al. Establishment of Tripterygium wilfordii Hook. f. Hairy root culture and optimization of its culture conditions for the production of triptolide and wilforine. J Microbiol Biotechnol. 2014 Jun 28;24(6):823-34.
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