Elevenostat ( JB3-22 )

Catalog No. M28876 CAS No. 1454902-97-6

Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Elevenostat
Note

Research use only, not for human use.
Brief Description

Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.
Description

Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.(In Vitro):Elevenostat induced cell death in MM cell lines.(In Vivo):Elevenostat produced similar anti-MM activity in vivo, improving survival among mice inoculated with 5TGM1 MM cells.
Synonyms

JB3-22
Pathway

Cell Cycle/DNA Damage
Target

HDAC
Recptor

Telomerase
Research Area

——
Indication

——

Chemical Information

CAS Number

1454902-97-6
Formula Weight

315.3
Molecular Formula

C16H17N3O4
Purity

>98% (HPLC)
Solubility

——
SMILES

COc(cccc1)c1NC(NCc(cc1)ccc1C(NO)=O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Fleming AM, et al. Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5'-Untranslated Regions. Biochemistry. 2018 Feb 13;57(6):991-1002.

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