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Elevenostat

CAS No. 1454902-97-6

Elevenostat( JB3-22 )

Catalog No. M28876 CAS No. 1454902-97-6

Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Elevenostat
  • Note
    Research use only, not for human use.
  • Brief Description
    Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.
  • Description
    Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235?μM.(In Vitro):Elevenostat induced cell death in MM cell lines.(In Vivo):Elevenostat produced similar anti-MM activity in vivo, improving survival among mice inoculated with 5TGM1 MM cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    JB3-22
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    Telomerase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1454902-97-6
  • Formula Weight
    315.32
  • Molecular Formula
    C16H17N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (792.85 mM)
  • SMILES
    COc(cccc1)c1NC(NCc(cc1)ccc1C(NO)=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fleming AM, et al. Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5'-Untranslated Regions. Biochemistry. 2018 Feb 13;57(6):991-1002.
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