EGLU( —— )

Catalog No. M32909 CAS No. 170984-72-2

EGLU ((2S)-α-Ethylglutamic acid) is a competitive mGluR-2 receptor antagonist with antidepressant activity and anti-injury effects, which can be used in the study of arthritis.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	445	Get Quote
5MG	686	Get Quote
10MG	938	Get Quote
25MG	1398	Get Quote
50MG	1822	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

EGLU
Note

Research use only, not for human use.
Brief Description

EGLU ((2S)-α-Ethylglutamic acid) is a competitive mGluR-2 receptor antagonist with antidepressant activity and anti-injury effects, which can be used in the study of arthritis.
Description

EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an?antidepressant agent.
In Vitro

EGLU (200 μM) selectively antagonizes (lS,3S)-ACPD-induced depressions of the monosynaptic component of the DRVRP, displaying little or no antagonist activity versus L-AP6 induced depressions or on the DRVRP alone.
In Vivo

——
Synonyms

——
Pathway

Neuroscience
Target

GluR
Recptor

GluR
Research Area

——
Indication

——

Chemical Information

CAS Number

170984-72-2
Formula Weight

175.18
Molecular Formula

C7H13NO4
Purity

>98% (HPLC)
Solubility

——
SMILES

[C@](CCC(O)=O)(C(O)=O)(CC)N
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Jane DE, et al. Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord.Neuropharmacology.?1996;35(8):1029-35.?

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