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EGLU

CAS No. 170984-72-2

EGLU( —— )

Catalog No. M32909 CAS No. 170984-72-2

EGLU ((2S)-α-Ethylglutamic acid) is a competitive mGluR-2 receptor antagonist with antidepressant activity and anti-injury effects, which can be used in the study of arthritis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    EGLU
  • Note
    Research use only, not for human use.
  • Brief Description
    EGLU ((2S)-α-Ethylglutamic acid) is a competitive mGluR-2 receptor antagonist with antidepressant activity and anti-injury effects, which can be used in the study of arthritis.
  • Description
    EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an?antidepressant agent.
  • In Vitro
    EGLU (200 μM) selectively antagonizes (lS,3S)-ACPD-induced depressions of the monosynaptic component of the DRVRP, displaying little or no antagonist activity versus L-AP6 induced depressions or on the DRVRP alone.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Neuroscience
  • Target
    GluR
  • Recptor
    GluR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    170984-72-2
  • Formula Weight
    175.18
  • Molecular Formula
    C7H13NO4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [C@](CCC(O)=O)(C(O)=O)(CC)N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jane DE, et al. Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord.Neuropharmacology.?1996;35(8):1029-35.?
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