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EG1

CAS No. 693241-54-2

EG1( —— )

Catalog No. M24706 CAS No. 693241-54-2

EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 133 In Stock
10MG 203 In Stock
25MG 410 In Stock
50MG 605 In Stock
100MG 852 In Stock
500MG 1701 In Stock
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Biological Information

  • Product Name
    EG1
  • Note
    Research use only, not for human use.
  • Brief Description
    EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.
  • Description
    EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.
  • In Vitro
    Cell Viability Assay Cell Line:Pax2 positive: a renal cell carcinoma line (RCC111), two ovarian carcinoma cell lines (TOV112D and ES-2); Pax2 negative: prostate cell lines 22Rv1, PC3 or the ovarian cancer cell line SK-OV-3 Concentration:0, 12.5, 25 μM Incubation Time:48 hours Result:All Pax2 positive cells exhibited a significant decrease in cell viability, whereas none of the Pax2 negative cells were affected.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Pax2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    693241-54-2
  • Formula Weight
    390.39
  • Molecular Formula
    C22H18N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:70mg/ml(179.31mM; need ultrasonic)
  • SMILES
    COc(cccc1)c1C(Nc(cc1)ccc1C(Nc(cccc1)c1C(O)=O)=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Smith CB, Phillips T, Smith TJ. Using the New ASCO Clinical Practice Guideline for Palliative Care Concurrent With Oncology Care Using the TEAM Approach. Am Soc Clin Oncol Educ Book. 2017;37:714-723. doi: 10.14694/EDBK_175474. PubMed PMID: 28561696.
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