Cart
sales@molnova.com
Home - Products - Angiogenesis - Bcl-2 - Disarib

Disarib

CAS No. 1998149-15-7

Disarib( —— )

Catalog No. M13120 CAS No. 1998149-15-7

Disarib is a novel BCL2-specific inhibitor that binds predominantly to the BH1 domain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Disarib
  • Note
    Research use only, not for human use.
  • Brief Description
    Disarib is a novel BCL2-specific inhibitor that binds predominantly to the BH1 domain.
  • Description
    Disarib is a novel BCL2-specific inhibitor that binds predominantly to the BH1 domain, demonstrates strong affinity to BCL2, but not to other antiapoptotic BCL2 family members(BCL-xL, BCL2A1 etc.); is a novel BCL2 inhibitor with a unique mechanism of BCL2 inhibition.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    Bcl-2
  • Recptor
    Bcl-2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1998149-15-7
  • Formula Weight
    547.855
  • Molecular Formula
    C26H16BrClN4OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    3-((2-(4-chlorobenzyl)-6-(4-bromophenyl)imidazo[2,1-b][1,3,4] -thiadiazol-5-yl)methylidene)-1,3-dihydro-2H-indol-2-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Iyer D, et al. FEBS J. 2016 Sep;283(18):3408-37. 2. Vartak SV, et al. Biochem Pharmacol. 2016 Dec 15;122:10-22. 3. Vartak SV, et al. Biochem Pharmacol. 2017 May 1;131:16-28. doi:
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Obatoclax

    A potent inhibitor of Bcl-2 family with IC50s of 1-7 uM for Bcl-2, Bcl-XL, Bcl-w, Bcl-B, Mcl-1 and Bfl-1.

  • SW076956

    SW076956 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.

  • Mcl1-IN-2

    Mcl1-IN-2 is an Mcl-1 inhibitor without a reported IC50 value.

Sign In Join Free