Cart
sales@molnova.com
Home - Products - Microbiology/Virology - Parasite - Diloxanide

Diloxanide

CAS No. 579-38-4

Diloxanide( RD 3803 | RD-3803 | RD3803 | Diloxanide | Diloxanid | Diloxanida )

Catalog No. M27976 CAS No. 579-38-4

Diloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 54 Get Quote
50MG 77 Get Quote
100MG 128 Get Quote
200MG 192 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Diloxanide
  • Note
    Research use only, not for human use.
  • Brief Description
    Diloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.
  • Description
    Diloxanide is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.
  • In Vitro
    ——
  • In Vivo
    Diloxanide is hydrolyzed in the gastrointestinal tract from its prodrug Diloxanide furoate.Diloxanide furoate (oral administraion; 75-200 mg/kg; 3 days; once daily) is effective at different dose of dayin weanling rats. At 200 mg/kg, 100% of the treated rats are cured and no amoebic lesions are observed in the caecum. Besides, 85%,77%, and 44.4% of the treated rats are cured at the dose 150 mg/kg, 100 mg/kg, and 75 mg/kg, respectively. The ED50 value is 77.9 mg/kg for this agent in rats.
  • Synonyms
    RD 3803 | RD-3803 | RD3803 | Diloxanide | Diloxanid | Diloxanida
  • Pathway
    Microbiology/Virology
  • Target
    Parasite
  • Recptor
    TNNI3 Interacting Kinase (TNNI3K)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    579-38-4
  • Formula Weight
    234.08
  • Molecular Formula
    C9H9Cl2NO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 33.33 mg/mL (142.39 mM)
  • SMILES
    CN(C(=O)C(Cl)Cl)c1ccc(O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Patterson JR, et, al. Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf. J Med Chem. 2021 Nov 11;64(21):15651-15670.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • UCB7362

    UCB7362 (GLXC-26743) is an orally available and potent plasmepsin X (PMX) inhibitor with anti-malarial activity.UCB7362 inhibits parasite reproduction.

  • N-(2-Hydroxypropyl)m...

    N-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.

  • Ganaplacide

    Ganaplacide (KAF156, GNF-156)?is a novel antimalarial clinical candidate that shows blood schizonticidal activity with IC50 of 6-17.4 nM against P falciparum drug-sensitive and drug-resistant strains.

Sign In Join Free