N-(2-Hydroxypropyl)methacrylamide
CAS No. 21442-01-3
N-(2-Hydroxypropyl)methacrylamide( —— )
Catalog No. M26312 CAS No. 21442-01-3
N-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 39 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameN-(2-Hydroxypropyl)methacrylamide
-
NoteResearch use only, not for human use.
-
Brief DescriptionN-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.
-
DescriptionN-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.(In Vivo):N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates (5 mg/kg) contains lysosomally degradable side chains and shows significant antileishmanial activity (>99% inhibition) in vivo .
-
In Vitro——
-
In VivoAt 5 mg/kg body weight drug equivalent dose, all N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates which contained lysosomally degradable side chains shows significant in vivo antileishmanial activity (>99% inhibition).
-
Synonyms——
-
PathwayMicrobiology/Virology
-
TargetParasite
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number21442-01-3
-
Formula Weight143.186
-
Molecular FormulaC7H13NO2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (698.42 mM)
-
SMILESCC(O)CNC(=O)C(C)=C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Cipargamin
Cipargamin (KAE609, NITD609) is a fast-acting, potent antimalarial agent that inhibits blood-stage activity in vitro against a panel of culture-adapted P. falciparum strains with IC50 of 0.5-1.4 nM.
-
Piperaquine
Piperaquine is a bis-quinoline compound that inhibits the ex vivo growth of P. falciparum isolates from malaria-infected patients with IC50s ranging from 11.8-217.3 nM.
-
Resorantel
Resorantel is a safe, hydroxybenzanilide cestocide moderately effective against Paramphistomum spp and highly effective against Thysaniezia spp. and Moniezia. Resorantel has been used for the research of G. aegypticus and is also used in the research of paramphistomiasis in cattle and sheep.
Cart
sales@molnova.com