N-(2-Hydroxypropyl)methacrylamide

CAS No. 21442-01-3

N-(2-Hydroxypropyl)methacrylamide( —— )

Catalog No. M26312 CAS No. 21442-01-3

N-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    N-(2-Hydroxypropyl)methacrylamide
  • Note
    Research use only, not for human use.
  • Brief Description
    N-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.
  • Description
    N-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.(In Vivo):N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates (5 mg/kg) contains lysosomally degradable side chains and shows significant antileishmanial activity (>99% inhibition) in vivo .
  • In Vitro
    ——
  • In Vivo
    At 5 mg/kg body weight drug equivalent dose, all N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates which contained lysosomally degradable side chains shows significant in vivo antileishmanial activity (>99% inhibition).
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Parasite
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    21442-01-3
  • Formula Weight
    143.186
  • Molecular Formula
    C7H13NO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (698.42 mM)
  • SMILES
    CC(O)CNC(=O)C(C)=C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Li Y, Wang CL, Guo SX, Yang JS, Xiao PG. Two new compounds from Dendrobium candidum. Chem Pharm Bull (Tokyo). 2008 Oct;56(10):1477-9.
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