Dapivirine

CAS No. 244767-67-7

Dapivirine ( TMC120 )

Catalog No. M13709 CAS No. 244767-67-7

Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 In Stock
5MG 71 In Stock
10MG 104 In Stock
25MG 169 In Stock
50MG 235 In Stock
100MG 318 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Dapivirine
  • Note
    Research use only, not for human use.
  • Brief Description
    Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM.
  • Description
    Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. Phase 3.
  • Synonyms
    TMC120
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV reverse transcriptase
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    244767-67-7
  • Formula Weight
    329.40
  • Molecular Formula
    C20H19N5
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 34 mg/mL (103.21 mM)
  • SMILES
    N#CC1=CC=C(NC2=NC=CC(NC3=C(C)C=C(C)C=C3C)=N2)C=C1
  • Chemical Name
    4-[[4-[(2,4,6-Trimethylphenyl)amino]-2-pyrimidinyl]amino]benzonitrile

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Van Herrewege Y, et al. Antimicrob Agents ChemOthers, 2004, 48(1), 337-339.
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