Cart
sales@molnova.com
DMJ-I-228
CAS No. 1374035-59-2
DMJ-I-228( +)-DMJ-I-228 )
Catalog No. M11542 CAS No. 1374035-59-2
A small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameDMJ-I-228
-
NoteResearch use only, not for human use.
-
Brief DescriptionA small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.
-
DescriptionA small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.
-
In Vitro——
-
In Vivo——
-
Synonyms+)-DMJ-I-228
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorHIV
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1374035-59-2
-
Formula Weight435.84
-
Molecular FormulaC19H19ClFN5O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(NC1=CC=C(Cl)C(F)=C1)C(N[C@@H]2[C@@H](NC(N)=N)CC3=C2C=CC=C3)=O.O=CO
-
Chemical NameN1-(4-chloro-3-fluorophenyl)-N2-((1S,2S)-2-guanidino-2,3-dihydro-1H-inden-1-yl)oxalamide formate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Madani N, et al. Structure. 2008 Nov 12; 16(11):1689-701.
2. Richard J, et al. Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2687-94.
3. LaLonde JM, et al. J Med Chem. 2012 May 10;55(9):4382-96.
molnova catalog
related products
-
MIV 150
A high-affinity, allosteric HIV-1 and HIV-2 reverse transcriptase inhibitor (NNRTI) with EC50 of 1 nM.
-
Dapivirine
Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM.
-
Ritonavir
A potent HIV protease inhibitor for treatment of HIV-1 infection.
