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SAMT-247

CAS No. 850715-59-2

SAMT-247( SAMT247 )

Catalog No. M16179 CAS No. 850715-59-2

SAMT-247 potent HIV-1 nucleocapsid protein NCp7 inhibitor with EC50 of 0.6 uM with low cellular toxicity (TC50>100 uM) in cultured and primary cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SAMT-247
  • Note
    Research use only, not for human use.
  • Brief Description
    SAMT-247 potent HIV-1 nucleocapsid protein NCp7 inhibitor with EC50 of 0.6 uM with low cellular toxicity (TC50>100 uM) in cultured and primary cells.
  • Description
    SAMT-247 potent HIV-1 nucleocapsid protein NCp7 inhibitor with EC50 of 0.6 uM with low cellular toxicity (TC50>100 uM) in cultured and primary cells; promotes covalent acetylation of Gag intracellularly, thereby blocking Gag processing and reducing infectivity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SAMT247
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    850715-59-2
  • Formula Weight
    266.32
  • Molecular Formula
    C12H14N2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(N)CCNC(C1=CC=CC=C1C(C)=O)=S
  • Chemical Name
    Ethanethioic acid,S-[2-[[(3-amino-3-oxopropyl)amino]carbonyl]phenyl] ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Miller Jenkins LM, et al. Nat Chem Biol. 2010 Dec;6(12):887-9.
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