Cart
sales@molnova.com
DDX3-IN-16d
CAS No. 1919828-83-3
DDX3-IN-16d ( —— )
Catalog No. M13009 CAS No. 1919828-83-3
A small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 1224 | Get Quote |
|
| 100MG | 1971 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameDDX3-IN-16d
-
NoteResearch use only, not for human use.
-
Brief DescriptionA small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3).
-
DescriptionA small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3), a human host factor required for the replication of several DNA and RNA viruses; shows a broad spectrum of antiviral activity with EC50 of 0.97-16.5 uM (HIV, HCV, DENV, and WNV), retaines full activity against HIV drug-resistant strains (EC50<1 uM); exhibts a good safety profile and bioavailability in rats.
-
Synonyms——
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorHIV
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1919828-83-3
-
Formula Weight307.36
-
Molecular FormulaC17H17N5O
-
Purity>98% (HPLC)
-
SolubilityDMSO : 125 mg/mL 406.70 mM; H2O : < 0.1 mg/mL
-
SMILESO=C(NC1=CC=C(N2N=NC(C)=C2)C=C1)NC3=CC=CC=C3C
-
Chemical Name1-(4-(4-Methyl-1H-1,2,3-triazol-1-yl)phenyl)-3-o-tolylurea
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Brai A, et al. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5388-93.
molnova catalog
related products
-
Raltegravir potassiu...
A potent, selective, orally bioavailable HIV-integrase inhibitor with IC50 of 15 nM.
-
RN-18
RN-18 is a small molecule that antagonizes HIV-1 Vif function and inhibits HIV-1 replication only in the presence of A3G.
-
Fosamprenavir calciu...
A phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility.
