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DDX3-IN-16d
CAS No. 1919828-83-3
DDX3-IN-16d( —— )
Catalog No. M13009 CAS No. 1919828-83-3
A small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 1224 | Get Quote |
|
| 100MG | 1971 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDDX3-IN-16d
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3).
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DescriptionA small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3), a human host factor required for the replication of several DNA and RNA viruses; shows a broad spectrum of antiviral activity with EC50 of 0.97-16.5 uM (HIV, HCV, DENV, and WNV), retaines full activity against HIV drug-resistant strains (EC50<1 uM); exhibts a good safety profile and bioavailability in rats.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research Area——
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Indication——
Chemical Information
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CAS Number1919828-83-3
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Formula Weight307.357
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Molecular FormulaC17H17N5O
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Purity>98% (HPLC)
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SolubilityDMSO : 125 mg/mL 406.70 mM; H2O : < 0.1 mg/mL
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SMILESO=C(NC1=CC=C(N2N=NC(C)=C2)C=C1)NC3=CC=CC=C3C
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Chemical Name1-(4-(4-Methyl-1H-1,2,3-triazol-1-yl)phenyl)-3-o-tolylurea
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Brai A, et al. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5388-93.
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