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Citalopram
CAS No. 59729-33-8
Citalopram( —— )
Catalog No. M33690 CAS No. 59729-33-8
Citalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine reuptake inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 28 | In Stock |
|
| 50MG | 38 | In Stock |
|
| 100MG | 58 | In Stock |
|
| 500MG | 138 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCitalopram
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NoteResearch use only, not for human use.
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Brief DescriptionCitalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine reuptake inhibitor.
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DescriptionCitalopram is a racemate mixture of the active S(+)-enantiomer (Escitalopram; HY-14258) and R(-)-enantiomer. Citalopram is an orally active selective serotonin reuptake inhibitor (SSRI). Citalopram is an antidepressant and enhances serotoninergic neurotransmission.
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In VitroCell Cytotoxicity Assay Cell Line:Rat B104, human SH-SY5Y, IMR32 and Kelly neuroblastoma cells Concentration:25, 50, 100, 125, 150, 175 μM Incubation Time:24 h Result:Showed a concentration-dependent cytotoxicity. RT-PCR Cell Line:B104 cells Concentration:100 μM Incubation Time:24 h Result:Strongly down-regulated MYBL2, BIRC5, BARD1, AURKA, CCNA2 and CCNE1 in B104 cells.
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In VivoAnimal Model:Male C57BL/6J and DBA/2J mice, aged 5-7 weeks, 16-20?g Dosage:5-40?mg/kg Administration:IP Result:Reduced immobility time in DBA/2J mice but not in C57BL/6J mice.
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Synonyms——
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number59729-33-8
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Formula Weight324.39
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Molecular FormulaC20H21FN2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (308.27 mM; Ultrasonic )
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SMILESCN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Carlsson B, et al. Enantioselective analysis of citalopram and escitalopram in postmortem blood together with genotyping for CYP2D6 and CYP2C19. J Anal Toxicol. 2009;33(2):65-76. ?
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