PF-04995274 ( PF-4995274;TBPT )

Catalog No. M11321 CAS No. 1331782-27-4

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Product Name

PF-04995274
Note

Research use only, not for human use.
Brief Description

PF-04995274 (TBPT) is a novel potent, sellective, partial agonist of 5-HT4 receptor under investigation for neurological disorders.
Description

PF-04995274 (TBPT) is a novel potent, sellective, partial agonist of 5-HT4 receptor under investigation for neurological disorders.Alzheimer Disease Phase 1 Discontinued
Synonyms

PF-4995274;TBPT
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

Neurological Disease
Indication

Alzheimer Disease

CAS Number

1331782-27-4
Formula Weight

432.52
Molecular Formula

C23H32N2O6
Purity

>98% (HPLC)
Solubility

——
SMILES

C1CN(CCC1COC2=NOC3=C2C(=CC=C3)OC4CCOC4)CC5(CCOCC5)O
Chemical Name

(R)-4-((4-(((4-(Tetrahydrofuran-3-yloxy)-1,2-benzisoxazol-3-yl)oxy)methyl)piperidin-1-yl)methyl)tetrahydro-2H-pyran-4-ol

1. Sawant-Basak A, et al. J Pharm Sci. 2013 Sep;102(9):3277-93.

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