Cenerimod ( ACT-334441 )

Catalog No. M11092 CAS No. 1262414-04-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Cenerimod
Note

Research use only, not for human use.
Brief Description

Cenerimod (ACT-334441) is a potent and orally available S1P1 receptor agonist with EC50 of 2.7 nM.
Description

Cenerimod (ACT-334441) is a potent and orally available S1P1 receptor agonist with EC50 of 2.7 nM; shows a powerful and long-lasting immunomodulating effect by reducing the number of circulating and infiltrating T- and B-lymphocytes, without affecting their maturation, memory, or expansion.Multiple Sclerosis Phase 1 Clinical
Synonyms

ACT-334441
Pathway

GPCR/G Protein
Target

Lysophospholipid Receptor
Recptor

Lysophospholipid Receptor
Research Area

Inflammation/Immunology
Indication

Multiple Sclerosis

CAS Number

1262414-04-9
Formula Weight

453.53
Molecular Formula

C25H31N3O5
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

OC[C@H](O)COC1=C(C)C=C(C2=NOC(C3=CC(C4CCCC4)=NC(OC)=C3)=N2)C=C1CC
Chemical Name

1,2-Propanediol, 3-[4-[5-(2-cyclopentyl-6-methoxy-4-pyridinyl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-, (2S)-