Carbaglu

CAS No. 1188-38-1

Carbaglu ( Carglumic Acid )

Catalog No. M10646 CAS No. 1188-38-1

Carglumic acid is an orphan drug used for the treatment of hyperammonaemia in patients with N-acetylglutamate synthase deficiency. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier and cause neurologic problems, cerebral edema, coma, and death.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
200MG 43 In Stock
500MG 80 In Stock
1G 107 In Stock

Biological Information

  • Product Name
    Carbaglu
  • Note
    Research use only, not for human use.
  • Brief Description
    Carglumic acid is an orphan drug used for the treatment of hyperammonaemia in patients with N-acetylglutamate synthase deficiency. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier and cause neurologic problems, cerebral edema, coma, and death.
  • Description
    Carglumic acid is an orphan drug used for the treatment of hyperammonaemia in patients with N-acetylglutamate synthase deficiency. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010.
  • Synonyms
    Carglumic Acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Carbamoyl-phosphate synthase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1188-38-1
  • Formula Weight
    190.15
  • Molecular Formula
    C6H10N2O5
  • Purity
    >98%(HPLC)
  • Solubility
    Water: 10 mM
  • SMILES
    O=C(O)[C@@H](NC(N)=O)CCC(O)=O
  • Chemical Name
    (2S)-2-(carbamoylamino)pentanedioic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Carglumic acid. Prescrire Int. 2008 Apr;17(94):50-
molnova catalog
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