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CCG-63808
CAS No. 620113-73-7
CCG-63808( —— )
Catalog No. M26641 CAS No. 620113-73-7
CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 56 | Get Quote |
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| 5MG | 87 | Get Quote |
|
| 10MG | 146 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameCCG-63808
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NoteResearch use only, not for human use.
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Brief DescriptionCCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins.
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DescriptionCCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. CCG-63808 dose-dependently inhibits the TR-FRET signal between RGS4-AF488 and Tb-Gαo with IC50 values of 1.9 μM.(In Vitro):CCG-63808 showed selectivity among RGS proteins with a potency order of RGS 4 > 19 = 16 > 8 7. CCG-63808 inhibited the GTPase accelerating protein activity of RGS4.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptormelanocortin 3 (MC3)| melanocortin-1 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number620113-73-7
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Formula Weight454.48
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Molecular FormulaC25H15FN4O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 1 mg/mL (2.20 mM)
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SMILESCc1cccn2c1nc(Oc1ccc(F)cc1)c(\C=C(/C#N)c1nc3ccccc3s1)c2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Montero-Melendez T, et al. Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects. J Immunol. 2015 Apr 1;194(7):3381-8.
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