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Canertinib

CAS No. 267243-28-7

Canertinib ( CI-1033; PD-183805 )

Catalog No. M18334 CAS No. 267243-28-7

Canertinib is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo.

Purity : 98%

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Biological Information

  • Product Name
    Canertinib
  • Note
    Research use only, not for human use.
  • Brief Description
    Canertinib is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo.
  • Description
    Canertinib is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET.
  • Synonyms
    CI-1033; PD-183805
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    EGFR; HER2/ErbB2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    267243-28-7
  • Formula Weight
    485.94
  • Molecular Formula
    C24H25ClFN5O3
  • Purity
    98%
  • Solubility
    DMSO : 4.9 mg/mL 10.08 mM;
  • SMILES
    C=CC(=O)Nc1c(cc2c(c1)c(ncn2)Nc1cc(c(cc1)F)Cl)OCCCN1CCOCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Smaill JB et al. J Med Chem. 2000; 43(7): 1380-1397.
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