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VH032-PEG4-NH2
CAS No. 2010159-57-4
VH032-PEG4-NH2( VH032-PEG4-NH2 | VHL Ligand-Linker Conjugates 4 | E3 ligase Ligand-Linker Conjugates 7 Free Base )
Catalog No. M26674 CAS No. 2010159-57-4
(S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 36 | In Stock |
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| 25MG | 73 | In Stock |
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| 50MG | 110 | In Stock |
|
| 100MG | 166 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameVH032-PEG4-NH2
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NoteResearch use only, not for human use.
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Brief Description(S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
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Description(S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
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In VitroE3 ligase Ligand-Linker Conjugates 7 Free Base, extracted from patent US20170008904A1, can be used in the synthesis of compound A1895 in example 3.
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In Vivo——
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SynonymsVH032-PEG4-NH2 | VHL Ligand-Linker Conjugates 4 | E3 ligase Ligand-Linker Conjugates 7 Free Base
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PathwayOthers
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TargetOther Targets
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RecptorAhR
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Research Area——
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Indication——
Chemical Information
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CAS Number2010159-57-4
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Formula Weight663.83
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Molecular FormulaC32H49N5O8S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 170 mg/mL (256.09 mM)
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SMILESO=C(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)COCCOCCOCCOCCN
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Cetyl glycol
Cetyl glycol favors the decomposition of the metal-organic precursor, formation of an intermediate Co(2+)Fe(3+)-oleate complex, and the nucleation of nanoparticles at lower temperatures. Cetyl glycol is a reducing agent that can be used in cosmetics.
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Isoquinoline
Isoquinoline is an analog of pyridine. Isoquinoline-based alkaloids, such as p-tolyl bisisoquinoline, phthaloyl isoquinoline, and naphthyl isoquinoline, exhibit anticancer activity.Berberine, an isoquinoline alkaloid, exerts anti-inflammatory effects in diabetic mice by downregulating the gene expression ratios of pro-/anti-inflammatory and Th1/Th2 cytokines.Additionally, some isoquinoline-based compounds also possess antidepressant, antibacterial, antimalarial, and anti-HIV activities.
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Borapetoside A
The stems of Tinospora crispa.
