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CK-37
CAS No. 1001478-90-5
CK-37( ChoK-α inhibitor CK37 )
Catalog No. M10017 CAS No. 1001478-90-5
A potent, specific, competitive inhibitor of choline kinase-α (Chok-α) by targeting the choline binding site.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCK-37
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, specific, competitive inhibitor of choline kinase-α (Chok-α) by targeting the choline binding site.
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DescriptionA potent, specific, competitive inhibitor of choline kinase-α (Chok-α) by targeting the choline binding site; significantly increases LC3II expression in MCF-7 and MCF-7/TAM cells, increases the size and number of autophagosome, causes MCF-7 and MCF-7/TAM cells to a slight increase in p62; suppresses MAPK and PI3K/AKT signaling, disrupts actin cytoskeletal organization, and reduces plasma membrane ruffling; significantly decreases tumor growth in a lung tumor xenograft mouse model, suppresses tumor phosphocholine, and diminishes activating phosphorylations of ERK and AKT in vivo.
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In Vitro——
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In Vivo——
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SynonymsChoK-α inhibitor CK37
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PathwayOthers
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TargetChoK
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RecptorChoK
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Research Area——
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Indication——
Chemical Information
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CAS Number1001478-90-5
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Formula Weight366.483
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Molecular FormulaC20H22N4OS
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Purity>98% (HPLC)
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Solubility——
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SMILESCCC1=CC=C(C=C1)C2=NC(=NN2)SCC(=O)NC3=CC(=CC(=C3)C)C
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Chemical NameN-(3,5-dimethylphenyl)-2-[[5-(4-ethylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl] acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Clem BF, et al. Oncogene. 2011 Jul 28;30(30):3370-80.
2. Kim HS, et al. PLoS One. 2015 Oct 23;10(10):e0141110.
3. Wong MT, et al. J Virol. 2016 Sep 29;90(20):9075-95.
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