Cart
sales@molnova.com
Home - Products - PROTACs - PROTAC - CDK9-PROTAC

CDK9-PROTAC

CAS No. 2118356-96-8

CDK9-PROTAC( CDK9PROTAC | CDK9 PROTAC | CDK9-PROTAC )

Catalog No. M13368 CAS No. 2118356-96-8

CDK9-PROTAC is a heterobifunctional small molecule PROTAC capable of cereblon mediated proteasomal degradation of CDK9.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 298 In Stock
10MG 478 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    CDK9-PROTAC
  • Note
    Research use only, not for human use.
  • Brief Description
    CDK9-PROTAC is a heterobifunctional small molecule PROTAC capable of cereblon mediated proteasomal degradation of CDK9.
  • Description
    CDK9-PROTAC is a heterobifunctional small molecule PROTAC capable of cereblon mediated proteasomal degradation of CDK9; selectively degrades CDK9 while sparing other CDK family members in HCT116 cells.
  • In Vitro
    PROTAC CDK9 Degrader-1 (Compound 3; 2.5-20 μM; 6 hours) degrades CDK9 in a dose dependent manner in HCT116 cells.Western Blot Analysis Cell Line:HCT116 cells Concentration:2.5, 5, 10, and 20μM Incubation Time:6 hours Result:Degraded CDK9 in a dose dependent manner.
  • In Vivo
    ——
  • Synonyms
    CDK9PROTAC | CDK9 PROTAC | CDK9-PROTAC
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    PROTAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2118356-96-8
  • Formula Weight
    613.671
  • Molecular Formula
    C33H35N5O7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 104 mg/mL 169.47 mM
  • SMILES
    O=C(NC1=NNC(C2CCC2)=C1)CC3=CC=C(OCCCCCOC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)C=C3
  • Chemical Name
    N-(5-cyclobutyl-1H-pyrazol-3-yl)-2-(4-((5-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)pentyl)oxy)phenyl)acetamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Robb CM, et al. Chem Commun (Camb). 2017 Jul 4;53(54):7577-7580.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • L-Azidohomoalanine h...

    L-Azidohomoalanine hydrochloride (H-L-Aha-OH hydrochloride) is an alkyl chain-based PROTAC linker.

  • FKBP12 PROTAC dTAG-7

    FKBP12 PROTAC dTAG-7 (dTAG-7) is a cell-permeable heterobifunctional adation tag (dTAG) small molecule that engage FKBP12F36V and CRBN.

  • DBCO-PEG4-NHS ester

    DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Sign In Join Free