EGNHS

CAS No. 70539-42-3

EGNHS( —— )

Catalog No. M33347 CAS No. 70539-42-3

EGNHS (EGS crosslinker) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
50MG 38 Get Quote
100MG 59 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    EGNHS
  • Note
    Research use only, not for human use.
  • Brief Description
    EGNHS (EGS crosslinker) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    EGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    PROTAC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    70539-42-3
  • Formula Weight
    456.36
  • Molecular Formula
    C18H20N2O12
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (219.13 mM; Ultrasonic )H2O : ≥ 4.17 mg/mL (9.14 mM)
  • SMILES
    OCC(=O)OC(=O)CC(N1C(=O)CCC1=O)C(=O)OCCOC(=O)C(CC(O)=O)N1C(=O)CCC1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
molnova catalog
related products
  • DD-03-171

    DD-03-171 is a small molecule, CGI1746-based BTK degrader (PROTAC, biochemical IC50=5.1 nM) that efficiently degrade C481S-BTK.

  • BETd-246

    A potent, second-generation BET protein degrader that exhibits superior selectivity, potency and antitumor activity.

  • MS4078

    MS4078 is a novel PROTAC (degrader) of ALK, potently decreases cellular levels of oncogenic active ALK fusion proteins in a concentration- and time-dependent manner in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells (DC50=11 nM).