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CD437
CAS No. 125316-60-1
CD437 ( CD437; CD 437; CD-437; Ro-472077 )
Catalog No. M17220 CAS No. 125316-60-1
CD437 is a specifc Retinoic Acid Receptor γ (RARγ) agonist.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
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| 5MG | 50 | In Stock |
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| 10MG | 80 | In Stock |
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| 25MG | 170 | In Stock |
|
| 50MG | 282 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCD437
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NoteResearch use only, not for human use.
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Brief DescriptionCD437 is a specifc Retinoic Acid Receptor γ (RARγ) agonist.
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DescriptionCD437 is a synthetic retinoid that is an RARγ-selective agonist. It displays RARγ-dependent and -independent effects on differentiation and apoptosis. CD437 induces apoptosis and acts synergistically with TRAIL receptor-2 agonist in malignant melanoma. CD437 inhibits DNA replication in cells and recombinant POLA1 activity in vitro.
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SynonymsCD437; CD 437; CD-437; Ro-472077
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PathwayMicrobiology/Virology
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TargetHBV
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RecptorRARγ
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number125316-60-1
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Formula Weight398.49
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Molecular FormulaC27H26O3
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Purity98%
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SolubilityDMSO : 150 mg/mL. 376.42 mM;
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SMILESO=C(C1=CC=C2C=C(C3=CC=C(O)C(C4(C5)CC6CC5CC(C6)C4)=C3)C=CC2=C1)O
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Chemical Name6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Li Y, et al. Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol. 1998 Aug;18(8):4719-31.
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