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Home - Products - Wnt/Notch/Hedgehog - Beta-catenin - CCT-031374

CCT-031374

CAS No. 442535-46-8

CCT-031374( CCT031374 )

Catalog No. M14506 CAS No. 442535-46-8

CCT-031374 is a selective β-catenin signaling inhibitor with IC50 of 6.1 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CCT-031374
  • Note
    Research use only, not for human use.
  • Brief Description
    CCT-031374 is a selective β-catenin signaling inhibitor with IC50 of 6.1 uM.
  • Description
    CCT-031374 is a selective β-catenin signaling inhibitor with IC50 of 6.1 uM; prevents BIO-induced accumulation of β-catenin, does not alter β-catenin levels but blocks transcription at the β-catenin level; also shows activity against endogenous LEF-1 mRNA levels in human neurogenic embryoid bodies (hNEBs) in which Wnt signaling had been induced by BIO.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CCT031374
  • Pathway
    Wnt/Notch/Hedgehog
  • Target
    Beta-catenin
  • Recptor
    Beta-catenin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    442535-46-8
  • Formula Weight
    353.425
  • Molecular Formula
    C23H19N3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1CN2C3=CC=CC=C3N(C2=N1)CC(=O)C4=CC=C(C=C4)C5=CC=CC=C5.Br
  • Chemical Name
    1-[1,1'-Biphenyl]-4-yl-2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)ethanone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ewan K, et al. Cancer Res. 2010 Jul 15;70(14):5963-73. 2. Yang Y, et al. Neuroscience. 2013 Sep 17;248:383-91. 3. Liu B, et al. Int J Mol Med. 2015 Dec;36(6):1572-82.
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