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CCG-224406
CAS No. 1870843-22-3
CCG-224406( CCG 224406 | CCG224406 )
Catalog No. M12895 CAS No. 1870843-22-3
A highly selective and potent GRK2 (G protein-coupled receptor kinase 2) inhibitor with IC50 of 130 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCCG-224406
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NoteResearch use only, not for human use.
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Brief DescriptionA highly selective and potent GRK2 (G protein-coupled receptor kinase 2) inhibitor with IC50 of 130 nM.
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DescriptionA highly selective and potent GRK2 (G protein-coupled receptor kinase 2) inhibitor with IC50 of 130 nM; displays >700-fold selectivity over other GRK subfamilies, and no detectable inhibition of ROCK1.
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In Vitro——
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In Vivo——
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SynonymsCCG 224406 | CCG224406
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PathwayOthers
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TargetGRK (GPCRK)
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RecptorGRK (GPCRK)
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Research Area——
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Indication——
Chemical Information
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CAS Number1870843-22-3
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Formula Weight558.57
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Molecular FormulaC29H27FN6O5
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1NC(C2=CC=C(F)C(C(NCC3=C(OC)C=CC=C3OC)=O)=C2)C(C(NC4=CC5=C(C=C4)NN=C5)=O)=C(C)N1
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Chemical Name4-(3-((2,6-dimethoxybenzyl)carbamoyl)-4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Waldschmidt HV, et al. J Med Chem. 2016 Apr 28;59(8):3793-807.
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