Cart
sales@molnova.com
GSK270822A
CAS No. 864082-23-5
GSK270822A( —— )
Catalog No. M34271 CAS No. 864082-23-5
GSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 340 | In Stock |
|
| 5MG | 332 | In Stock |
|
| 10MG | 440 | In Stock |
|
| 25MG | 667 | In Stock |
|
| 50MG | 876 | In Stock |
|
| 100MG | 1172 | In Stock |
|
| 200MG | 1562 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGSK270822A
-
NoteResearch use only, not for human use.
-
Brief DescriptionGSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.
-
DescriptionRho-Kinase-IN-3 (compound 12) is a potent and selective Rho kinase (ROCK1) inhibitor with an IC50 value of 8 nM. Rho-Kinase-IN-3 can be used in research of hypertension.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetGRK (GPCRK)
-
RecptorGRK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number864082-23-5
-
Formula Weight396.44
-
Molecular FormulaC24H20N4O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(NC=1C=C2C(=CC1)NN=C2)(=O)C=3C(CC(=O)NC3C)C4=CC5=C(C=C4)C=CC=C5
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Goodman KB, et, al. Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors. J Med Chem. 2007 Jan 11;50(1):6-9.?
molnova catalog
related products
-
1-(2,3-DIHYDRO-BENZO...
1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.
-
GRK6-IN-2
GRK6-IN-2 is a potent G protein-coupled receptor kinase 6 (GRK6) inhibitor with potential antitumor activity.GRK6-IN-2 has been studied in multiple myeloma.
-
CCG-215022
CCG-215022 (CCG215022) is a potent and selective pan GRK inhibitor with IC50 of 0.15/0.38/3.9 uM for GRK2/5/1 respectively.
