CBP-IN-1

CAS No. 2222941-37-7

CBP-IN-1( —— )

Catalog No. M22843 CAS No. 2222941-37-7

CBP-IN-1 is a potent inhibitor of p300/CBP bromodomain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 84 In Stock
5MG 140 In Stock
10MG 250 In Stock
25MG 528 In Stock
50MG 755 In Stock
100MG 1017 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    CBP-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    CBP-IN-1 is a potent inhibitor of p300/CBP bromodomain.
  • Description
    CBP-IN-1 is a potent inhibitor of p300/CBP bromodomain.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Noncastrated male athymic nude mice Dosage:10-30 mg/kg Administration:Oral gavage; at 10 or 20 mg/kg daily (QD) or at 30 mg/kg every other day (QOD) for 28 days Result:Affected tumor growth at 10 mg/kg daily, 20 mg/kg daily, and 30 mg/kg every other day.
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Epigenetic Reader Domain
  • Recptor
    p300/CBP
  • Research Area
    cancer
  • Indication
    Haematological Malignancy|Acute Myeloid Leukemia|Non Hodgkin Lymphoma|Multiple Myeloma

Chemical Information

  • CAS Number
    2222941-37-7
  • Formula Weight
    534.6
  • Molecular Formula
    C30H32F2N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (187.06 mM; Need ultrasonic)
  • SMILES
    O=C1N(C2=CC=C(F)C(F)=C2)[C@H](C3=NC4=CC(C5=C(C)ON=C5C)=CC=C4N3[C@H]6CC[C@H](OC)CC6)CCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Neil Anthony Pegg, et al. Pharmaceutical compounds. WO2018073586A1.
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