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CASIN

CAS No. 425399-05-9

CASIN ( CASIN )

Catalog No. M17507 CAS No. 425399-05-9

CASIN is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 41 In Stock
5MG 61 In Stock
10MG 111 In Stock
25MG 178 In Stock
50MG 267 In Stock
100MG 412 In Stock
500MG 888 In Stock
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Biological Information

  • Product Name
    CASIN
  • Note
    Research use only, not for human use.
  • Brief Description
    CASIN is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).
  • Description
    CASIN is an inhibitor of Cdc42 GTPase, a small GTPase of the Rho-subfamily that plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo.
  • Synonyms
    CASIN
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Integrin
  • Recptor
    STAT3
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    425399-05-9
  • Formula Weight
    306.41
  • Molecular Formula
    C20H22N2O
  • Purity
    98%
  • Solubility
    DMSO : ≥ 31 mg/mL; 101.17 mM
  • SMILES
    C1CC(c2c(C1)c1c([nH]2)ccc(c1)c1ccccc1)NCCO
  • Chemical Name
    2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Li Y,et al. Suppression of cancer relapse and metastasis by inhibiting cancer stemness. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1839-44.
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