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C5-benzyl SAHA
CAS No. 2115700-64-4
C5-benzyl SAHA ( —— )
Catalog No. M13367 CAS No. 2115700-64-4
C5-benzyl SAHA is a C5-modified SAHA analog that displays dual selectivity to HDAC.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameC5-benzyl SAHA
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NoteResearch use only, not for human use.
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Brief DescriptionC5-benzyl SAHA is a C5-modified SAHA analog that displays dual selectivity to HDAC.
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DescriptionC5-benzyl SAHA is a C5-modified SAHA analog that displays dual selectivity to HDAC6 (IC50=0.27 uM) and HDAC8 (IC50=0.38 uM) over HDAC 1, 2, and 3 (IC50=2.9-5.8 uM); dose dependently and selectively increases in levels of acetyl-α-tubulin in U937 leukemia cells.
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research Area——
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Indication——
Chemical Information
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CAS Number2115700-64-4
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Formula Weight354.45
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Molecular FormulaC21H26N2O3
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name4-benzyl-N8-hydroxy-N1-phenyloctanediamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Negmeldin AT, et al. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3254-3258.
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